The Best my.cnf for Percona 5.7

[mysql]
socket = /var/run/mysql/mysql.sock

[mysqld]
user = mysql

bind-address = 0.0.0.0
port = 3306

basedir = /usr/local/mysql
pid-file = /var/run/mysql/mysql.pid
socket = /var/run/mysql/mysql.sock
datadir = /var/data/mysql
tmpdir = /tmp

# Log Path
#lc-messages-dir = /var/log/mysql
#lc_messages = en_US
log-error = /var/log/mysql/error.log


explicit_defaults_for_timestamp
skip-name-resolve

sql_mode = NO_ENGINE_SUBSTITUTION,STRICT_TRANS_TABLES
symbolic-links = 0

max_allowed_packet              = 16M
max_connect_errors              = 1000000


thread_stack                    = 192K
thread_cache_size               = 50
max_connections                 = 500
#max_heap_table_size            = 2G
#tmp_table_size                 = 2G
table_open_cache                = 16384
table_definition_cache          = 16384
open_files_limit                = 65536
#key_buffer_size                = 512M
query_cache_type                = 0
#default_storage_engine         = TokuDB
#default_tmp_storage_engine     = TokuDB


# Innodb Settings
innodb_buffer_pool_size                         = 12G
innodb_buffer_pool_instances                    = 8
innodb_buffer_pool_dump_at_shutdown             = 1
innodb_buffer_pool_load_at_startup              = 1
innodb_flush_method                             = O_DIRECT
innodb_log_files_in_group                       = 2
innodb_log_file_size                            = 4G
innodb_flush_log_at_trx_commit                  = 0
innodb_change_buffering                         = all
# innodb_additional_mem_pool_size               = 32M
innodb_file_per_table                           = 1
innodb_read_io_threads                          = 16
innodb_write_io_threads                         = 16
innodb_io_capacity                              = 50000
#innodb_log_buffer_size                         = 16M
innodb_thread_concurrency                       = 0
#innodb_lock_wait_timeout                       = 120
innodb_open_files                               = 65536
innodb_autoinc_lock_mode                        = 1
#innodb_log_write_ahead_size                    = 4096
innodb_flush_neighbors                          = 0


#tokudb_loader_memory_size                      = 10G
#tokudb_directio                                = 1
#tokudb_cache_size                              = 25G
#tokudb_commit_sync                             = OFF
#tokudb_fsync_log_period                        = 1000
#tokudb_analyze_in_background                   = ON
#tokudb_analyze_mode                            = TOKUDB_ANALYZE_RECOUNT_ROWS


# BINARY LOGGING #
#log-bin = /var/data/mysql/mysql-bin
#sync-binlog                    = 1
#expire-logs-days               = 14

# Slow Query Log
#slow_query_log_file = /var/log/mysql/slow-query.log
slow_query_log                  = 0
long_query_time                 = 3